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    CUBIST

    CUBIST

    Audio | Defense Health Agency

    About

    Clinical Updates in Brain Injury Science Today, or “CUBIST,” is a podcast for health care providers about current research on traumatic brain injury.



    Episodes


    • CUBIST S8E11: Measuring Reaction Time Accuracy in Military TBI Assessment Tools

      In this episode of CUBIST, the host discusses a study titled “Accuracy of Reaction Time Measurement on Automated Neuropsychological Assessment Metric UltraMobile," published in the journal Archives of Clinical Neuropsychology in September of 2024. Jacques Arrieux, a contractor in support of TBICoE, a research scientist at Fort Liberty, and the lead author of the study, joins the podcast.

      Article Citation: Arrieux, J., & Ivins, B. (2024). Accuracy of Reaction Time Measurement on... read more

      11/19/2024


    • CUBIST S8E10: Post-Traumatic Headache and Depression After Mild TBI

      In this episode of CUBIST, the host discusses a study titled "Relationship Between Post-Traumatic Headache and Depression After Mild Traumatic Brain Injury," by Dr. Marissa Beal and colleagues, published in the Journal of Neuropsychiatry and Clinical Neurosciences in August 2024.

      Article Citation: Beal, M. L., Psoter, K. J., Bechtold, K. T., Nagpaul, V., Peters, M. E., Rao, V., Van Meter, T. E., Falk, H., Korley, F. K., & Roy, D. (2024). Relationship Between Posttraumatic Headache and... read more

      10/25/2024


    • CUBIST S8E9: Exploring Benzodiazepine Risks in Military TBI Treatment

      In this episode of CUBIST, the host discusses a study titled “Prescription Patterns After Mild Traumatic Brain Injury in U.S. Military Service Members,” written by Lauren Earyes and her colleagues at TBICoE and published in Military Medicine in July 2024. In addition, Ms. Earyes, lead author and health systems specialist at TBICoE, joins the podcast.

      Article Citation: Earyes, L., Agimi, Y., & Stout, K. (2024). Benzodiazepine Prescription Patterns After Mild Traumatic Brain Injury in... read more

      10/02/2024


    • CUBIST S8E8: Impact of Symptom Reporting on Sport Concussion Diagnosis

      In this episode of CUBIST, the host discusses a study titled "Diagnosis of Sports-Related Concussion Using Symptom Report or Standardized Assessment of Concussion" by Dr. Kimberly Harmon and colleagues and published in JAMA Network Open in June 2024.

      Article Citation: Harmon, K. G., Whelan, B. M., Aukerman, D. F., Hwang, C. E., Poddar, S. K., DeLeo, A., Elkington, H. A., Garruppo, G., Holliday, M., & Bruce, J. M. (2024). Diagnosis of Sports-Related Concussion Using Symptom Report or... read more

      08/21/2024


    • CUBIST S8E7: Exploring Gender Differences in TBI Outcomes

      In this episode of CUBIST, the host discusses a study titled "Gender Disparities in Neurobehavioral Symptoms and the Role of Post-Traumatic Symptoms in US Service Members Following Mild Traumatic Brain Injury" by Dr. Ida Babakhanyan and colleagues, published in the Journal of Neurotrauma in April 2024. In addition, the lead author and senior research neuropsychologist, Dr. Babakhanyan, joins the podcast.

      Article Citation: Babakhanyan, I., Brickell, T. A., Bailie, J. M., Hungerford, L.,... read more

      07/30/2024


    • CUBIST S8E6: Evaluating Branched-Chain Amino Acids for Concussion Treatment

      In this episode of CUBIST, the hosts discuss a study titled “Head Injury Treatment with Healthy and Advanced Dietary Supplements, a pilot randomized controlled trial of the tolerability, safety, and efficacy of branched chain amino acids in the treatment of concussion in adolescents and young adults.” The study was authored by Dr. Daniel Corwin and his colleagues. and was published in the Journal of Neurotrauma in April of 2024.

      Article Citation: Corwin, D. J., Myers, S. R., Arbogast,... read more

      06/24/2024


    • CUBIST S8E5: Can Blast Exposure Have an Effect on Gut Health?

      In this episode of CUBIST, the hosts discuss a study titled "Association of Blast Exposure and Military Breaching with Intestinal Permeability Blood Biomarkers Associated with Leaky Gut” by Qingkun Liu and colleagues and published in the International Journal of Molecular Sciences in March 2024. In addition, Dr. Phil Karl joins the podcast. Dr. Karl is a government service employee serving as a nutritional physiologist with the military nutrition division at the U. S. Army Research... read more

      05/20/2024


    • CUBIST S8E4: Can Spectral Filters be Used to Treat Persistent Photophobia and Headaches After TBI?

      In this episode of CUBIST, the hosts discuss a study titled "Individualized Spectral Filters Alleviate Persistent Photophobia, Headaches, and Migraines in Active Duty Military and Veterans Following Brain Trauma" by Sandra Tosta and colleagues and published in Brain Injury in February 2024.

      Article Citation: Tosta, S., Ferreira, M., Lewine, J., & Anderson, A. (2024). Individualized spectral filters alleviate persistent photophobia, headaches and migraines in active duty military and... read more

      04/30/2024


    • CUBIST S8E3: Exploring TES in Community-Dwelling Older Adults

      In this episode of CUBIST, Dr. Don Marion and Dr. Kati Monti discuss a study titled “Examining the New Consensus Criteria for Traumatic Encephalopathy Syndrome in Community-Dwelling Older Adults” by Douglas Terry and colleagues and published in the Journal of Neurotrauma in January 2024.

      Article Citation: Terry, D. P., Jo, J., Williams, K., Davis, P., Iverson, G. L., & Zuckerman, S. L. (2024). Examining the New Consensus Criteria for Traumatic Encephalopathy Syndrome in... read more

      03/26/2024


    • CUBIST S8E2: Early Intervention Treatment Strategies

      In this episode of CUBIST, Dr. Keith Stuessi and Dr. Kati Monti discuss a study titled "Early Intervention Treatment in the First Two Weeks Following Concussion in Adults: A Systematic Review of Randomized Controlled Trials” by Dr. Sonia Moore and colleagues and published in Physical Therapy in Sport in January 2024.

      Article Citation: Moore, S., Musgrave, C., Sandler, J., Bradley, B., & Jones, J. R. A. (2024). Early intervention treatment in the first 2 weeks following concussion in... read more

      02/23/2024


    • CUBIST S8E1: Transforming TBI Assessment with Augmented Reality

      In this episode of CUBIST, Don and Kati discuss a study entitled "Development of the Troop Readiness Evaluation with Augmented Reality Return to Duty or Troop READY Platform to Aid in the Detection and Treatment of Military Mild Traumatic Brain Injury" by Dr. Anson Rosenfeldt and colleagues and published in Military Medicine in November 2023.

      Article Citation: Rosenfeldt, A. B., Kaya, R. D., Owen, K., Hastilow, K., Scelina, K., Scelina, L., Miller Koop, M., Zimmerman, E., & Alberts, J. L.... read more

      01/17/2024


    • CUBIST S7E5: The Impact of Lifetime Blast Exposure on Neurobehavioral Outcomes Following Mild TBI

      In this episode of CUBIST, Dr. Keith Stuessi and Dr. Kati Monti discuss a study entitled “High Lifetime Blast Exposure Using the Blast Exposure Threshold Survey is Associated with Worse Warfighter Brain Health Following Mild Traumatic Brain Injury” by Dr. Rael Lange and colleagues and published in the Journal of Neurotrauma in October 2023. In addition, we've invited Dr. Lange, a clinical researcher at TBICoE and the lead author of the paper, to comment on their findings.

      Article... read more

      12/26/2023


    • CUBIST S7E4: Can Blast Exposure Throughout a Military Career Impact TBI Recovery?

      In this episode of CUBIST, Dr. Don Marion and new host, Dr. Keith Stuessi, discuss a study entitled "Cumulative Blast Exposure During a Military Career Negatively Impacts Recovery from Traumatic Brain Injury" by Dr. Jason Bailie and colleagues, published in the Journal of Neurotrauma in September 2023. Dr. Bailie, a neuropsychologist at TBICoE, joins the program to discuss the study investigating the impact of cumulative blast exposure on the recovery from TBI among military... read more

      11/14/2023


    • CUBIST S7E3: TBI and Long-Term Stroke Risk in Veterans

      In this episode of CUBIST, Amanda, and Don discuss the article “Traumatic brain injury and long-term risk of stroke among U.S. military service members," written by Andrea Schneider and her colleagues and published in the journal Stroke in August of 2023. In addition, a senior biostatistician at TBICoE, Mr. Brian Ivins, helps decipher some of the biostatistical issues that were raised by this study.

      Article Citation: Schneider, A. L. C., Peltz, C. B., Li, Y., Bahorik, A., Gardner, R.... read more

      10/16/2023


    • CUBIST S7E2: Exploring Links Between Health Behaviors and TBI Recovery in Service Members

      In this episode of CUBIST, Amanda, and Don discuss the article, “Associations between health-related behaviors and self-reported cognitive symptoms in U.S. military personnel injured on deployment.” This article was written by Sarah Jurek and colleagues and published in the Journal of Psychiatric Research in August of 2023.

      Sleep Disturbances Following Concussion, and other TBICoE clinical resources: health.mil/TBIProviders

      Article Citation: Jurick, S. M., McCabe, C. T., Watrous,... read more

      09/12/2023


    • CUBIST S7E1: How the Glymphatic System and TBI May Impact Cognitive Function

      In this episode of CUBIST, Amanda, and Don discuss the article, “Associations of MRI derived glymphatic system impairment with global white matter damage and cognitive impairment in mild traumatic brain injury: A DTI-ALPS study” by Dianne Zhu Yang and colleagues and published in the Journal of Magnetic Resonance Imaging in June of 2023.

      Article Citation: Yang, D. X., Sun, Z., Yu, M. M., Zou, Q. Q., Li, P. Y., Zhang, J. K., Wu, X., Li, Y. H., & Wang, M. L. (2023). Associations of... read more

      08/15/2023


    • CUBIST S6E10: Depression, Post-Traumatic Stress, and Performance: Mild TBI in Service Members

      In this episode of CUBIST, Amanda, and Don discuss the article, “Impact of Depression and Post-Traumatic Stress on Manual and Ocular Motor Performance in Service Members with a history of mild traumatic brain injury." An article written by Dr. Lars Hungerford and colleagues, published in the journal Brain Injury in May of 2023. Additionally, we are thrilled to welcome Dr. Lars Hungerford, a senior clinical research director at TBICoE in San Diego.

      Article Citation: Hungerford, L.,... read more

      07/12/2023


    • CUBIST S6E9: Can symptom clusters provide new insights into concussion management?

      In this episode of CUBIST, Amanda and Don discuss the article, “Primary and secondary risk factors associated with concussion symptom clusters in collegiate athletes: Results from the NCAA-DoD Grand Alliance Care Consortium" written by Kate Nolan and her colleagues and published in the Journal Brain Injury in April, 2023.

      Article Citation: Nolan, K. E., Caccese, J. B., Kontos, A. P., Buckley, T. A., Garcia, G. P., Port, N., Broglio, S. P., McAllister, T. W., McCrea, M., Pasquina, P. F.,... read more

      06/14/2023


    • CUBIST S6E8: Decision-Making Tools for TBI Diagnosis in Austere Environments

      In this episode of CUBIST, Amanda and Don discuss the article, “Validation of the Canadian CT Head Rule and the New Orleans Criteria for mild traumatic brain injury in Ethiopia” by Yegeta Habte and colleagues and published in World Neurotrauma in April of 2023.

      Article Citation: Habte, Y. W., Pajer, H. B., Abicho, T. B., Feleke, Y., Bizuneh, Y. A., Shao, B., & Spader, H. S. (2023). Validation of the Canadian CT Head Rule and the New Orleans Criteria for Mild Traumatic Brain Injury in... read more

      05/15/2023


    • CUBIST S6E7: Mild TBI vs. Concussion: Understanding Patient Perception

      In this episode of CUBIST, Amanda, and Don discuss the article, “Comparison of self-reported lifetime concussions and mild traumatic brain injuries among adults,” by Jill Doherty and colleagues and published in the Journal of Brain Injury in February of 2023.

      Article Citation: Daugherty, J., Sarmiento, K., & Breiding, M. (2023). Comparison of self-reported lifetime concussions and mild traumatic brain injuries among adults. Brain injury, 1–8. Advanced online publication.... read more

      04/19/2023


    • CUBIST S6E6: Evaluating Media Attention on CTE

      In this episode of CUBIST, Amanda and Don discuss the article, "Telling the whole story: Bibliometric network analysis to evaluate impact of media attention on chronic traumatic encephalopathy research," by Sean Eagle and Dave Okonkwo and published in the Journal of Neurotrauma in January of 2023.

      Article Citation: Eagle, S. R., & Okonkwo, D. O. (2023). Telling the Whole Story: Bibliometric Network Analysis to Evaluate Impact of Media Attention on Chronic Traumatic Encephalopathy... read more

      03/16/2023


    • CUBIST S6E5: Battlefield to Recovery: Combating Comorbid TBI Headaches and PTSD with CBT

      In this episode of CUBIST, Amanda, and Don discuss the article, "Cognitive behavioral therapy for veterans with comorbid post-traumatic headache and post-traumatic stress disorder symptoms: A randomized clinical trial" by Donald McGeary and colleagues and published in JAMA Neurology in August of 2022.

      Article Citation: McGeary, D. D., Resick, P. A., Penzien, D. B., McGeary, C. A., Houle, T. T., Eapen, B. C., Jaramillo, C. A., Nabity, P. S., Reed, D. E., 2nd, Moring, J. C., Bira, L. M.,... read more

      02/15/2023


    • CUBIST S6E4: TBI Symptom Burden and the Importance of Early Identification for Clinical Trial Design

      In this episode of CUBIST, Amanda and Don discuss the article, "Risk Factors for high symptom burden three months after traumatic brain Injury and implications for clinical trial design: A TRACK-TBI study” by Nancy Temkin and colleagues published in the Journal of Neurotrauma in June of 2022.

      Article Citation: Temkin, N., Machamer, J., Dikmen, S., Nelson, L. D., Barber, J., Hwang, P. H., Boase, K., Stein, M. B., Sun, X., Giacino, J., McCrea, M. A., Taylor, S. R., Jain, S., Manley, G., &... read more

      01/30/2023


    • CUBIST S6E3: The Effects of Physical Exertion on Biomarker Changes

      In this episode of CUBIST, Amanda and Don interview Dr. Jeff Bazarian, the principal investigator of the article, "Effects of physical exertion on early changes in blood-based brain biomarkers: implications for the acute point of care diagnosis of concussion" and published in the Journal of Neurotrauma in October, 2022.

      Article Citation:
Bazarian, J. J., Abar, B., Merchant-Borna, K., Pham, D. L., Rozen, E., Mannix, R., Kawata, K., Chou, Y., Stephen, S., & Gill, J. M. (2022). Effects... read more

      12/29/2022


    • CUBIST S6E2: Is history of mTBI linked to abnormal neuroendocrine disorder screens?

      In this episode of CUBIST, Amanda and Don discuss the article, "Relation of mild traumatic brain injury history to abnormalities on a preliminary neuroendocrine screen; a Multi-Center LIMBIC-CENC Analysis,” by Bill Walker and colleagues and published in Brain Injury in May of 2022.

      Article Citation: Walker, W. C., Werner, J., Agyemang, A., Allen, C., Resch, J., Troyanskaya, M., & Kenney, K. (2022). Relation of Mild Traumatic Brain Injury history to abnormalities on a preliminary... read more

      11/17/2022


    • CUBIST S6E1: Clinical Benefits of Near Infrared Devices

      In this episode of CUBIST, Amanda and Don discuss the article, "Clinical utility of near-infrared device in detecting traumatic intracranial hemorrhage: a pilot study toward application as an emergent diagnostic modality in a low-resource setting,” an article written by Robert Gramer and colleagues and published in the Journal of Neurotrauma in August of 2022.

      Article Citation:
      Gramer, R., Shlobin, N. A., Yang, Z., Niedzwiecki, D., Haglund, M. M., & Fuller, A. T. (2022). Clinical... read more

      10/26/2022


    • CUBIST S5E10: Bright light therapy for veterans with TBI

      In this episode of CUBIST, Amanda and Don discuss the article, "Feasibility and preliminary efficacy for morning bright light therapy to improve sleep and plasma biomarkers in US veterans with TBI," by Jonathan Elliot and colleagues and published in the journal PLOS One in April of 2021.

      Article Citation:
      Elliott, J. E., McBride, A. A., Balba, N. M., Thomas, S. V., Pattinson, C. L., Morasco, B. J., Wilkerson, A., Gill, J. M., & Lim, M. M. (2022). Feasibility and preliminary efficacy for... read more

      09/07/2022


    • CUBIST S5E9: Is there a relationship between PTSD symptoms and tinnitus severity?

      In this episode of CUBIST, Amanda and Don discuss the article, "PTSD symptoms and tinnitus severity: An analysis of veterans with post-traumatic headaches,” by John Moring and colleagues and published in the Journal of Health Psychology in March of 2022.

      Article Citation:
      Moring, J. C., Straud, C. L., Penzien, D. B., Resick, P. A., Peterson, A. L., Jaramillo, C. A., Eapen, B. C., McGeary, C. A., Mintz, J., Litz, B. T., Young-McCaughan, S., Keane, T. M., & McGeary, D. D. (2022). PTSD... read more

      08/18/2022


    • CUBIST S5E8: Implementation Strategies of TBI Clinical Care Guidelines

      In this episode of CUBIST, Amanda and Don discuss the article entitled "Review of implementation concepts and strategies surrounding traumatic brain injury clinical care guidelines," published in the Journal of Neurotrauma in December of 2021.

      Article Citation:
      Lumba-Brown, A., Prager, E. M., Harmon, N., McCrea, M. A., Bell, M. J., Ghajar, J., Pyne, S., & Cifu, D. X. (2021). A Review of Implementation Concepts and Strategies Surrounding Traumatic Brain Injury Clinical Care Guidelines.... read more

      07/14/2022


    • CUBIST S5E7: Insomnia Trajectories After TBI

      In this episode of CUBIST, Amanda and Don interview Dr. Emerson Wickwire, the principal investigator of the article, "Trajectories of insomnia and adults after traumatic brain injury," published in JAMA in January of 2022.

      Article Citation:
      Wickwire, E. M., Albrecht, J. S., Capaldi, V. F., 2nd, Jain, S. O., Gardner, R. C., Werner, J. K., Mukherjee, P., McKeon, A. B., Smith, M. T., Giacino, J. T., Nelson, L. D., Williams, S. G., Collen, J., Sun, X., Schnyer, D. M., Markowitz, A. J.,... read more

      05/13/2022


    • CUBIST S5E6: Can low resilience after TBI affect neurobehavioral functioning?

      In this episode of CUBIST, our hosts discuss the article, ““Entitled low resilience following traumatic brain injury is strongly associated with poor neural behavioral functioning in U. S. military service members and veterans,” by Victoria Merit and colleagues and published in the Journal Brain Injury, February 2022. 

      Article Citation:
      Merritt, V. C., Brickell, T. A., Bailie, J. M., Hungerford, L., Lippa, S. M., French, L. M., & Lange, R. T. (2022). Low resilience following... read more

      05/10/2022


    • CUBIST S5E5: Persistent TBI symptoms due to blasts

      In this episode of CUBIST, our hosts discuss the article, “The Persistence of Blast-Versus Impact Induced Concussion Symptomatology Following Deployment,” an article written by Jennifer Belding and colleagues and published in the Journal of Head Trauma Rehabilitation in December of 2021.

      Article Citation:
      Belding, J. N., Khokhar, B., Englert, R. M., Fitzmaurice, S., & Thomsen, C. J. (2021). The Persistence of Blast- Versus Impact-Induced Concussion Symptomology Following Deployment.... read more

      02/01/2022


    • CUBIST S5E4: Gender differences in TBI treatment and outcomes

      In this episode of CUBIST, our hosts discuss the article, “Differences between men and women in treatment and outcomes after traumatic brain injury” by Ana Mikolic and colleagues, and published in the Journal of Neurotrauma in October of 2020. Don and Amanda also interview Col. Jennifer Gurney, a surgeon with the U.S. Army Institute of Surgical Research and chair of the Defense Committees on Trauma.

      Article Citation:
      Mikolić, A., van Klaveren, D., Groeniger, J. O., Wiegers, E.,... read more

      01/10/2022


    • CUBIST S5E3: TBI characteristics in special operators and conventional service members

      In this episode of CUBIST, Amanda, and Don discuss the article, “Health conditions among Special Operations Forces versus conventional military service members of VA TBI model systems ”a study by Amanda Garcia and colleagues and published in the Journal of Head Trauma and Rehabilitation, October 2021. 

      Article Citation:
      Garcia, A., Kretzmer, T. S., Dams-O'Connor, K., Miles, S. R., Bajor, L., Tang, X., Belanger, H. G., Merritt, B. P., Eapen, B., McKenzie-Hartman, T., & Silva, M. A.... read more

      10/04/2021


    • CUBIST S5E2: Detecting movement differences in tactical agility tests using wearable technology

      In this episode of CUBIST, Amanda, and Don discuss the article, “Wearable sensors detect movement differences in the portable warrior test of tactical agility after mTBI in service members” by Oleg Favorov and colleagues, and published in Military Medicine in September of 2021

      Article Citation:
      Favorov, O., Kursun, O., Challener, T., Cecchini, A., & McCulloch, K. L. (2021). Wearable Sensors Detect Movement Differences in the Portable Warrior Test of Tactical Agility After mTBI in... read more

      09/06/2021


    • CUBIST S5E1: Can a device effectively predict if CT scans are necessary while deployed?

      In this episode of CUBIST, Amanda, and Don discuss the article, “Accuracy of a rapid GFAP/UCH-L1 test for the prediction of intracranial injuries on head CT after mild traumatic brain injury” by Jeff Bazarian and colleagues, and published in Academic Emergency Medicine, August 2021.

      Article Citation:
      Bazarian, J. J., Welch, R. D., Caudle, K., Jeffrey, C. A., Chen, J. Y., Chandran, R., McCaw, T., Datwyler, S. A., Zhang, H., & McQuiston, B. (2021). Accuracy of a rapid glial fibrillary... read more

      08/09/2021


    • CUBIST S4E10: Is cognitive rehab effective regardless of the number of concussions?

      In this episode of CUBIST, Amanda, and Don discuss the article, “Number of concussions does not affect treatment response to cognitive rehabilitation interventions following mild traumatic brain injury in military service members.” The study was authored by Anna Ord and her colleagues and was published in the Journal of Neurotrauma in July 2021.

      Article Citation:
      Ord, A. S., Shura, R. D., Curtiss, G., Armistead-Jehle, P., Vanderploeg, R. D., Bowles, A. O., Kennedy, J. E., Tate, D.... read more

      05/03/2021


    • CUBIST S4E8: Blast-related mild TBI impacts on visual disturbances

      In this episode of CUBIST, Amanda, and Don discuss the article, “Blast mild traumatic brain injury is associated with increased myopia and chronic convergence insufficiency” by Francesca C. Fortenbaugh and colleagues, published in Vision Research published in May, 2021.

      Article Citation:
      Fortenbaugh, F. C., Gustafson, J. A., Fonda, J. R., Fortier, C. B., Milberg, W. P., & McGlinchey, R. E. (2021). Blast mild traumatic brain injury is associated with increased myopia and chronic... read more

      04/08/2021


    • CUBIST S4E7: Changes in brain network connections following TBI in Special Operation Forces

      In this episode of CUBIST, Amanda, and Don discuss the article, “Characterizing changes in network connectivity following chronic head trauma in Special Forces military personnel: a combined resting-fMRI and DTI study” by Allen Champagne and colleagues, published in Brain Injury in April 2021.

      Article Citation:
      Champagne, A. A., Coverdale, N. S., Ross, A., Murray, C., Vallee, I., & Cook, D. J. (2021). Characterizing changes in network connectivity following chronic head trauma in... read more

      04/07/2021


    • CUBIST S4E6: TBI and the risk of sleep disorder

      In this episode of CUBIST, Don and Amanda discuss the article, “Traumatic Brain Injury and Incidence Risk of Sleep Disorders in Nearly 200,000 US Veterans,” written by Yue Leng and colleagues and published in Neurology in March of 2021. For more information on treating sleep disorders after TBI, check out our Sleep Clinical Recommendation at Health.mil/TBIProviders.

      Article Citation:
      Leng, Y., Byers, A. L., Barnes, D. E., Peltz, C. B., Li, Y., & Yaffe, K. (2021). Traumatic Brain... read more

      04/06/2021


    • CUBIST S4E5: Predictive Accuracy of TBI Screening Tools

      In this episode of CUBIST, Amanda and Don discuss the article, “Predictive Accuracy of the Sport Concussion Assessment Tool 3 and Vestibular/Ocular-Motor Screening, Individually and In Combination: A National Collegiate Athletic Association–Department of Defense Concussion Assessment, Research and Education Consortium Analysis” written by Lyndsey Ferris and colleagues, and was published in the American Journal of Sports Medicine in February 2021.

      Article Citation:
      Ferris, L. M.,... read more

      04/05/2021


    • CUBIST S4E4: Multidisciplinary approaches to TBI and psychological care

      In this episode of CUBIST, Amanda and Don discuss the article, “Efficacy of an Interdisciplinary Intensive Outpatient Program in Treating Combat-Related Traumatic Brain Injury and Psychological Health Conditions,” written by Thomas DeGraba and his colleagues at the National Intrepid Center of Excellence, and was published in the journal Frontiers in Neurology January of 2021.

      Article Citation:
      DeGraba, T. J., Williams, K., Koffman, R., Bell, J. L., Pettit, W., Kelly, J. P., Dittmer,... read more

      02/04/2021


    • CUBIST S4E3: Recovery Profiles After Concussion

      In this episode of CUBIST, Amanda and Don discuss the article, “Recovery Profiles after Concussion Among Male Student-Athletes and Service Cadets with a Family History of Neurodegenerative Disease: Data from the NCAA-DoD CARE Consortium,” written by Adam Harrison and colleagues. The article was published in the Journal of Neurotrauma in December of 2020.

      Article Citation: Harrison, A. T., McAllister, T., McCrea, M., Broglio, S. P., Moore, R. D., & CARE Consortium Investigators (2021).... read more

      02/03/2021


    • CUBIST S4E2: Blast exposure estimators

      In this episode of CUBIST, Amanda and Don discuss the article, “Development of a Blast Exposure Estimator from a DOD-Wide Survey Study on Military Service Members,” written by Lieutenant Claire M. Modica and colleagues. The article was published in the Journal of Neurotrauma in November of 2020.”

      Article Citation:
      Modica, L., Egnoto, M. J., Statz, J. K., Carr, W., & Ahlers, S. T. (2021). Development of a Blast Exposure Estimator from a Department of Defense-Wide Survey Study on... read more

      02/02/2021


    • CUBIST S4E1: Improving concussion education

      In this episode of CUBIST, Amanda and Don discuss the article, “Improving concussion education: consensus from the NCAA-Department of Defense Mind Matters Research & Education Grand Challenge.” by Emily Kroshus and her colleagues published in the British Journal of Sports Medicine in September of 2020.

      Article Citation:
      Kroshus, E., Cameron, K. L., Coatsworth, J. D., D'Lauro, C., Kim, E., Lee, K., ... & Silverman, R. D. (2020). Improving concussion education: consensus from the... read more

      02/01/2021


    • CUBIST S3E12: Analysis of Concussion Assessment Tools

      In this episode of CUBIST, Don, and Amanda discuss the article, “Sideline Concussion Assessment: The Current State of the Art” by John Yue and colleagues, published in the journal Neurosurgery, September 2020.

      Article Citation:
      Yue, J. K., Phelps, R., Chandra, A., Winkler, E. A., Manley, G. T., & Berger, M. S. (2020). Sideline Concussion Assessment: The Current State of the Art. Neurosurgery, 87(3), 466–475. https://doi.org/10.1093/neuros/nyaa022

      Article LINK:... read more

      10/02/2020


    • CUBIST S3E11: Lasting consequences of concussion on the aging brain

      In this episode of CUBIST, Don, and Amanda discuss the article,
      “Lasting consequences of concussion on the aging brain: Findings from the Baltimore Longitudinal Study of Aging” published in the Journal of Neuroimage in July of 2020.

      Article Citation:
      June, D., Williams, O. A., Huang, C. W., An, Y., Landman, B. A., Davatzikos, C., ... & Beason-Held, L. L. (2020). Lasting consequences of concussion on the aging brain: Findings from the Baltimore Longitudinal Study of Aging.... read more

      10/01/2020


    • CUBIST S3E10: Self-Reported TBI Symptoms During Deployment

      In this episode of CUBIST, Don, and Amanda discuss the article,
      “Self-Reported Concussion Symptomology during Deployment: Differences as a Function of Injury Mechanism and Low-Level Blast Exposure” published in the Journal of Neurotrauma in May of 2020.

      Article Citation:
      Belding, J. N., Fitzmaurice, S., Englert, R. M., Koenig, H. G., Thomsen, C. J., & Olaghere da Silva, L. U. (2020). Self-Reported Concussion Symptomology during Deployment: Differences as a Function of Injury... read more

      07/01/2020


    • CUBIST S3E9: Sleep-Wake Disturbances and TBI Recovery

      In this episode of CUBIST, Don and Amanda discuss the article, “The Prevalence and Stability of Sleep-Wake Disturbance and Fatigue Throughout the First Year After Traumatic Brain Injury” published in the Journal of Neurotrauma in May of 2020.

      Article Citation:
      Saksvik, S. B., Karaliute, M., Kallestad, H., Follestad, T., Asarnow, R., Vik, A., Håberg, A. K., Skandsen, T., & Olsen, A. (2020). The Prevalence and Stability of Sleep-Wake Disturbance and Fatigue throughout the First Year... read more

      06/24/2020


    • CUBIST S3E8: Sleep Disturbances and TBI Recovery

      In this special episode of CUBIST, Amanda, and special guests Dr. Joanne Gold and Stacey Harcum, talk about the newly revised clinical recommendation "Sleep Disturbances Following Concussion/mTBI: Guidance for the Primary Care Manager in Deployed and Non-Deployed Settings."

      The new Sleep Clinical Recommendation can be found here: Health.mil/TBIProviders

      CUBIST is a podcast for health care providers produced by the Traumatic Brain Injury Center of Excellence. We discuss the latest research on traumatic brain injury (TBI) most relevant to patient care. For more about TBI, including clinical tools, go to Health.mil/TBICoE or email us at dha.TBICoEinfo@mail.mil.

      05/01/2020


    • CUBIST S3E7: Neuroendocrine Function and Associated Mental Health Outcomes Following Mild TBI

      In this episode of CUBIST, Don and Amanda discuss the article, “Neuroendocrine function and associated mental health outcomes following mild traumatic brain injury in OEF-deployed service members.”

      Article Citation:
      Ciarlone, S. L., Statz, J. K., Goodrich, J. A., Norris, J. N., Goforth, C. W., Ahlers, S. T., & Tschiffely, A. E. (2020). Neuroendocrine function and associated mental health outcomes following mild traumatic brain injury in OEF-deployed service members. Journal of... read more

      04/28/2020


    • CUBIST S3E6: Alterations in Plasma MicroRNA and Protein Levels in Veterans with Chronic TBI

      In this episode of CUBIST, Don and Amanda discuss the article, “Alterations in plasma microRNA and protein levels in War Veterans with chronic mild traumatic brain injury.”

      Article Citation:
      Ghai, V., Fallen, S., Baxter, D., Scherler, K., Kim, T. K., Zhou, Y., ... & Cook, D. G. (2020). Alterations in plasma microRNA and protein levels in War Veterans with chronic mild traumatic brain injury. Journal of neurotrauma

      CUBIST is a podcast for health care providers produced by the... read more

      03/27/2020


    • CUBIST S3E5: Delayed Clinic Visits Following Concussion and Association to Recovery

      In this episode of CUBIST, our hosts discuss the article, “Association of time since injury to the first clinic visit with recovery following concussion.”

      Article Citation:
      Kontos, A. P., Jorgensen-Wagers, K., Trbovich, A. M., Ernst, N., Emami, K., Gillie, B., ... & Collins, M. W. (2020). Association of Time Since Injury to the First Clinic Visit With Recovery Following Concussion. JAMA Neurology.

      CUBIST is a podcast for health care providers discussing the latest research on... read more

      03/02/2020


    • CUBIST S3E4: Expedited Symptom Resolution After a Concussion

      On this episode of CUBIST, our host discusses the article entitled “Use of the Progressive Return to Activity Guidelines may expedite symptom resolution after concussion for active duty Military” with lead author, Dr. Jason Bailie. The study was published in the December 2019 issue of the American Journal of Sports Medicine.

      Reference Citation:
      Bailie, J. M., Remigio-Baker, R. A., Cole, W. R., McCulloch, K. L., Ettenhofer, M. L., West, T., ... & Mullins, L. (2019). Use of the... read more

      02/06/2020


    • CUBIST S3E3: Injuries Associated with Electric-Powered Bikes and Scooters

      In this episode of CUBIST, our hosts discuss the article, “Injuries associated with electric-powered bikes and scooters: Analysis of US consumer product data.”

      Article Citation: DiMaggio, C. J., Bukur, M., Wall, S. P., Frangos, S. G., & Wen, A. Y. (2019). Injuries associated with electric-powered bikes and scooters: Analysis of US consumer product data. Injury Prevention, injuryprev-2019-043418. doi.org/10.1136/injuryprev-2019-043418

      CUBIST is a podcast for health care providers... read more

      01/28/2020


    • CUBIST S3E2: Influences of Chronic Cigarette Smoking on Neurocognitive Recovery after TBI

      In this episode of CUBIST, Betsy and Don discuss the article, “The Influence of Chronic Cigarette Smoking on Neurocognitive Recovery after Mild Traumatic Brain Injury.”

      Reference Citation: Durazzo, T. C., Abadjian, L., Kincaid, A., Bilovsky-Muniz, T., Boreta, L., & Gauger, G. E. (2013). The influence of chronic cigarette smoking on neurocognitive recovery after mild traumatic brain injury. Journal of neurotrauma, 30(11), 1013-1022.

      CUBIST is a podcast for health care providers... read more

      12/10/2019


    • CUBIST S3E1: Suicide and TBI Among Veterans Seeking VA Health Care

      In the first episode of the third season of CUBIST, Betsy and Don discuss the article, “Suicide and Traumatic Brain Injury Among Individuals Seeking Veterans Health Administration Services Between Fiscal Years 2006 and 2015.”

      Reference Citation: Hostetter, T. A., Hoffmire, C. A., Forster, J. E., Adams, R. S., Stearns-Yoder, K. A., & Brenner, L. A. (2019). Suicide and traumatic brain injury among individuals seeking Veterans Health Administration services between fiscal years 2006 and... read more

      11/26/2019


    • CUBIST S1E12: Assessing concussion in high school athletes

      Dr. Don Marion and Dr. Anne Bunner discuss concussion assessment methods for high school athletes.

      Publication: Currie, D.W., Kraeutler, M.J., Schrock, J.B., McCarty, E.C., Comstock, R.D. (2017). Time Trends in Concussion Symptom Presentation and Assessment Methods in High School Athletes. American Journal of Sports Medicine, 45(14), 3368-3373. doi: 10.1177/0363546517725068

      PubMed link: www.ncbi.nlm.nih.gov/pubmed/28930492

      CUBIST is a podcast for health care providers produced by... read more

      07/12/2018


    • CUBIST S1E11: Effect of memantine on moderate TBI

      Dr. Don Marion and Dr. Anne Bunner discuss whether a drug known for treating Alzheimer’s, which may have some neuroprotective effects, could improve short-term neurological function in patients with moderate TBI.

      Publication: Mokhtari, M., Nayeb-Aghaei, H., Kouchek, M., Miri, M.M., Goharani, R., Amoozandeh, A., Akhavan Salamat, S., Sistanizad, M. (2017). Effect of Memantine on Serum Levels of Neuron-Specific Enolase and on the Glasgow Coma Scale in Patients With Moderate Traumatic Brain... read more

      07/11/2018


    • CUBIST S1E10: Sport related concussion and NCATs

      Dr. Don Marion and Dr. Anne Bunner discuss the use of neurocognitive assessment tests following sport-related concussions.

      Publication: Alsalaheen, B., Stockdale, K., Pechumer, D., Broglio, S.P., & Marchetti, G.F. (2017). A Comparative Meta-Analysis of the Effects of Concussion on a Computerized Neurocognitive Test and Self-Reported Symptoms. Journal of Athletic Training, 52(9): 834-846. doi.org/10.4085/1062-6050-52.7.05

      Journal link:... read more

      06/18/2018


    • CUBIST S1E9: Sport concussion and neuroimaging

      Dr. Don Marion and Dr. Anne Bunner discuss neuroimaging evidence of altered brain structure and function in concussed athletes with longer recovery times.

      Publication discussed: Churchill, N.W., Hutchison, M.G., Richards, D., Leung, G., Graham, S.J., & Schweizer, T.A. (2017). Neuroimaging of sport concussion: persistent alterations in brain structure and function at medical clearance.
      Scientific Reports 7, article number 8297. doi:10.1038/s41598-017-07742-3

      Nature publications link:... read more

      06/09/2018


    • CUBIST S1E8: Can you get a brain injury from riding a roller coaster?

      Dr. Don Marion and Dr. Anne Bunner discuss a study on the effects of roller coaster rides on the brain.

      Publication discussed: Kuo, C., Wu, L.C., Ye, P.P., Laksari, K., Camarillo, D.B., Kuhl E. (2017). Pilot Findings of Brain Displacements and Deformations during Roller Coaster Rides. Journal of Neurotrauma, epub ahead of print. doi: 10.1089/neu.2016.4893

      PubMed link: www.ncbi.nlm.nih.gov/pubmed/28683585

      CUBIST is a podcast for health care providers produced by the Traumatic Brain... read more

      05/21/2018


    • CUBIST S1E7: Cortical thickness, age and TBi

      Dr. Don Marion and Dr. Anne Bunner discuss objective and quantifiable imaging markers of traumatic brain injury in relation to aging.

      Publication discussed: Savjani RR, Taylor BA, Acion L, Wilde EA, & Jorge R. Accelerated Changes in Cortical Thickness Measurements with Age in Military Service Members with Traumatic Brain Injury. J Neurotrauma. 2017 Jun 28. doi: 10.1089/neu.2017.5022. [Epub ahead of print]

      PubMed link: www.ncbi.nlm.nih.gov/pubmed/28657432

      CUBIST is a podcast for... read more

      05/07/2018


    • CUBIST S1E6: Depression, gender and traumatic brain injury

      Dr. Anne Bunner and Dr. Don Marion discuss a study comparing rates of depression in men and women following a traumatic brain injury (TBI).

      Publication discussed: Lavoie, S., Sechrist, S., Quach, N., Ehsanian, R., Duong, T., Gotlib, I. H., & Isaac, L. (2017). Depression in Men and Women One Year Following Traumatic Brain Injury (TBI): A TBI Model Systems Study. Frontiers in Psychology, (8)634, eCollection. doi: 10.3389/fpsyg.2017.00634

      PubMed link:... read more

      05/06/2018


    • CUBIST S1E5: Sport concussion consensus statement

      Dr. Anne Bunner discusses recent updates to 2012 guidelines from the Concussion in Sport Group, also known as the “Berlin consensus statement” on sport concussion.

      Publication discussed: McCrory P, Meeuwisse W, Dvořák J, et al. Consensus statement on concussion in sport—the 5th international conference on concussion in sport held in Berlin, October 2016. Br J Sports Med 2017;51:838-847.

      CUBIST is a podcast for health care providers produced by the Traumatic Brain Injury... read more

      05/05/2018


    • CUBIST S1E4: Wearable sensors to detect head impact

      Dr. Don Marion and host Inbal Eshel consider a study on the usefulness of wearable sensors to measure head impacts.

      Publication discussed: Cortes, N., Lincoln, A., Myer, G.D., Hepburn, L., Higgins, M., Putukian, M., & Caswell S. (2017). Video analysis verification of head impact events measured by wearable sensors. American Journal of Sports Medicine. Published online. DOI: 10.1177/0363546517706703

      PubMed link: www.ncbi.nlm.nih.gov/pubmed/28541813

      CUBIST is a podcast for health care... read more

      05/04/2018


    • CUBIST S1E3: Outcome predictors for blast TBI

      Dr. Anne Bunner discusses a study about early predictors of long-term outcomes following blast-related concussion.

      Publication discussed: MacDonald C.L., Barber, J., Jordan, M., Johnson, A.M., Dikmen, S., Fann, J.R., & Temkin N. (2017). Early clinical predictors of 5-year outcome after concussive blast traumatic brain injury. JAMA Neurology. Advance online publication. doi: 10.1001/jamaneurol.2017.0143.

      PubMed link: www.ncbi.nlm.nih.gov/pubmed/28459953

      Link to interview with... read more

      05/03/2018


    • CUBIST S1E2: Concussion and neurocognitive assessment tools

      Dr. Don Marion discusses two new studies about neurocognitive assessment tools, or NCATs

      Publications discussed: Cole WR, Arrieux JP, Schwab K, Ivins BJ, Qashu FM, Lewis SC. Test-Retest Reliability of Four Computerized Neurocognitive Assessment Tools in an Active Duty Military Population. Arch Clin Neuropsychol. 2013 Nov;28(7):732-42. doi: 10.1093/arclin/act040. Epub 2013 Jul 2.

      PubMed link: www.ncbi.nlm.nih.gov/pubmed/23819991

      Cole WR, Arrieux JP, Ivins BJ, Schwab KA, Qashu FM. A... read more

      05/02/2018


    • CUBIST S1E1: Concussion, genetics and alzheimers

      Dr. Anne Bunner discusses research on how genetics and traumatic brain injury (TBI) interact to impact Alzheimer’s disease risk.

      Publication discussed: Hayes JP, Logue MW, Sadeh N, et al. Mild traumatic brain injury is associated with reduced cortical thickness in those at risk for Alzheimer's disease. Brain. 2017;140(3):813-825. doi: 10.1093/brain/aww344

      CUBIST is a podcast for health care providers produced by the Traumatic Brain Injury Center of Excellence. We discuss the latest... read more

      05/01/2018